Modern understanding of the brain’s ability to adapt and rewire itself was transformed by discoveries made by Mriganka Sur and V.S. Ramachandran. In 1988, Sur demonstrated that regions of the brain traditionally associated with hearing could process visual information, challenging assumptions about fixed brain function. Ramachandran later developed mirror therapy to treat phantom limb pain, revealing the brain’s remarkable capacity for reorganization. Together, their work reshaped neuroscience and influenced rehabilitation, neurotechnology, and brain-computer interface research.