Anandi Gopal Joshi was a medical pioneer who became the first Indian woman to earn a Western medical degree, graduating from the Woman’s Medical College of Pennsylvania in 1886 at the age of 21. Her thesis explored obstetrics in Hindu society, reflecting an early exchange of medical knowledge between India and the United States. At a time when few women pursued higher education, she overcame formidable social and cultural barriers to study medicine abroad. Her achievement inspired generations of women to pursue careers in medicine and strengthened early academic ties between the two countries.